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Design and engineering of TRAIL fusion proteins for cancer therapy
MM-151 elicits broad and unique inhibition of cells harboring EGFR extracellular domain mutations —results of multiscale experiments with genome-edited cell lines
A network biology screen reveals ligand-receptor pathway connections and resistance mechanisms to RTK-directed therapies in cancer cells
HER2-targeted PEGylated liposomal doxorubicin (MM-302) efficiently targets the HER2 intermediate cell population in vitro and in vivo
Istiratumab (MM-141), a bispecific antibody targeting IGF-1R and ErbB3, inhibits pro-survival signaling in vitro and potentiates the activity of standard of care chemotherapy in vivo in ovarian cancer models
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